For example, assuming Brood War stats, if a Drone is holding Minerals while Morphing into a Creep Colony, it would cost only 67 Minerals, instead of the usual 75.
The Zerg could use this slight advantage, considering they lose a worker in the process.
It could also help a LOT in the situations like losing your only Hatchery to a focused rush early in a team game, and surviving with 8-or-fewer Minerals short of 300, but still having a few Drones left with a mineral chunk in their mandibles.
Maybe the Terran SCVs and Protoss Probes could adapt this as well, after seeing how it plays out.